Scytalone

Scytalone

$240.00 - 1 mg

$840.00 - 5 mg

All prices in Australian dollars

Code
BIA-S3074
Synonyms
(+)-Scytalone, Scytalon
CAS #
49598-85-8
Molecular Formula
C10H10O4
Molecular Weight
194.2
Purity
>95% by HPLC
Long Term Storage
Soluble in methanol and DMSO.

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Application Notes

Scytalone is a trihydroxytetralone first isolated from Scytaladium sp. by Findlay and Kwan, University of New Brunswick, Canada in 1972. Scytalone has subsequently been isolated from a large number of species of diverse fungal genera. Scytalone is a pivotal intermediate of melanin biosynthesis in fungi and is considered to play an integral role in spore structural development and protecting spores from biotic and abiotic stresses.

References

  • Findlay J.A. & Kwan D. (1973). Scytalone (3,6,8-trihydroxytetralone), a metabolite from a Scytalidium species. Can. J. Chem., 51, 1617.
  • Bell A.A. et al. (1976). Pentaketide metabolites of Verticillium dahliae. Identification of (+)-scytalone as a natural precursor to melanin. Tetrahedron, 32, 1353.
  • Zhang P. et al. (2017). A cryptic pigment biosynthetic pathway uncovered by heterologous expression is essential for conidial development in Pestalotiopsis fici. Mol. Microbiol., 105, 469.

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