Protoporphyrin, disodium salt

Protoporphyrin, disodium salt

$230.00 - 25 mg

$65.00 - 5 mg

All prices in Australian dollars

Code
BIA-P2300
Synonyms
Depocolin S, Disodium protoporphyrin, Prolmon
CAS #
50865-01-5
Molecular Formula
C34H34N4O4.Na2
Molecular Weight
606.6
Purity
>95% by HPLC
Long Term Storage
Soluble in methanol or DMSO

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Application Notes

Protoporphyrin disodium is the salt of protoporphyrin, an endogenous metabolite of living organisms. Protoporphyrin is a photosensitizer. Protoporphyrin is a branch point in the biosynthetic pathway leading to haem by insertion of iron and chlorophylls by insertion of Mg and further side-chain transformation. Protoporphyrin and its derivatives are active against human immunodeficiency virus.

References

  • Biosynthesis of the pigments of life: formation of the macrocycle. Battersby A.R. et al. Nature 1980, 285, 1.
  • Reduced gene expression at the branch point of chlorophyll and heme biosynthesis in Arctic Chlorella ArM0029B. Vikramathithan J. et al. Plant Biotechnol Rep. 2017, 11, 9.
  • In vitro studies on the protoporphyrin uptake and photosensitivity of normal skin fibroblasts and fibroblasts from patients with erythropoietic protoporphyria. Schothorst A.A. et al. J Invest Derm. 1977, 69, 551.
  • Anti-​HIV activity of protoporphyrin. Asanaka M. et al. AIDS 1989, 3, 403.
  • Modeling of anti-​HIV-​1 activity of a diverse set of porphyrin derivatives. Vanyur R. et al. Magyar Kemiai Folyoirat, Kemiai Kozlemenyek 2004, 109, 71.

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