Piliformic acid

Piliformic acid

$215.00 - 0.50 mg

$755.00 - 2.50 mg

All prices in Australian dollars

Code
BIA-P2269
Synonyms
(2E)-2-Hexylidene-3-methylbutanedioic acid
CAS #
98985-76-3
Molecular Formula
C11H18O4
Molecular Weight
214.26
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in methanol or DMSO

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Product Data Sheet

Application Notes

Piliformic acid is produced by fungi including Xylaria sp.. Piliformic acid has mild inhibitory activity against Propionobacterium acnes, inhibiting the P. acnes-induced pro-inflammatory cytokines production in THP-1 cells. Piliformic acid is active against the plant fungal pathogen Colletotrichum gloeosporioides with MIC 2.92 μmol/mL and has antileishmanial activity.

References

  • Metabolites of the higher fungi. Part 22. 2-Butyl-3-methylsuccinic acid and 2-hexylidene-3-methylsuccinic acid from xylariaceous fungi. Anderson J.R. et al. J Chem Soc Perkin Trans. 1 1985, 1481.
  • Leishmanicidal compounds of Nectria pseudotrichia, an endophytic fungus isolated from the plant Caesalpinia echinata (Brazilwood). Barros Cota B. et al. Mem Inst Oswaldo Cruz. 2018, 113, 102.
  • The potential of compounds isolated from Xylaria spp. as antifungal agents against anthracnose. Elias L.M. et al. Braz J Microbiol. 2018, 49, 840.

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