Phe-L-Pro, L-

Phe-L-Pro, L-

$90.00 - 5 mg

$315.00 - 25 mg

All prices in Australian dollars

Code
BIA-P2369
Synonyms
L-Phenylalanyl-L-proline
CAS #
7669-65-0
Molecular Formula
C14H18N2O3
Molecular Weight
262.3
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in methanol or DMSO

Download Data Sheets

Product Data Sheet

Application Notes

L-Phe-L-Pro (phenylalanylproline) is a dipeptide isolated from Streptomyces lavendulae no. 314. L-Phe-L-Pro is an incomplete breakdown product of protein catabolism. L-Phe-L-Pro demonstrates cholesterol-lowering activity in hypercholesterolemic rats via decreased ATP-binding cassette transporter A1 (ABCA1) expression in the rat jejunum and reduced cholesterol absorption in Caco-2 cells.

References

  • Diketopiperazines containing L-proline from Streptomyces lavendulae and their stereochemistry in solution. Kubo A. et al. Experientia 1977, 33, 12.
  • Identification of a novel cholesterol-lowering dipeptide, phenylalanine-proline (FP), and its down-regulation of intestinal ABCA1 in hypercholesterolemic rats and Caco-2 cells. Banno A. et al. Sci Rep. 2019, 9, 19416.

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