Norfunalenone
Application Notes
Norfunalenone, the demethyl analogue of funalenone, is isolated from Aspergillus sp.. The bioprofile of norfunalenone is not well investigated, however funalenone is a novel inhibitor of collagenase and inhibitor of HIV-1 integrase.
References
- Funalenone, a novel collagenase inhibitor produced by Aspergillus niger. Inokoshi J. et al. J Antibiot. 1999, 52, 1095.
- Targeting the MraY and MurG bacterial enzymes for antimicrobial therapeutic intervention. Zawadzke L.E. Anal Biochem. 2003, 314, 243.
- Fungal phenalenones inhibit HIV-1 integrase. Shiomi K. et al. J Antibiot. 2005, 58, 65.