Massoialactone

Massoialactone

$230.00 - 25 mg

$65.00 - 5 mg

All prices in Australian dollars

Code
BIA-M2571
Synonyms
Massoilactone, Massoya lactone
CAS #
54814-64-1
Molecular Formula
C10H16O2
Molecular Weight
168.23
Purity
>95% by HPLC
Long Term Storage
Soluble in methanol or DMSO

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Product Data Sheet

Application Notes

Massoialactone is a constituent of Melicope sp., a large genus of more than 200 species occurring in the Pacific islands, Asia, Australia and New Zealand, also isolated from other plant and insect sources. Massoialactone Is a moderately potent inhibitor of the growth of Aspergillus niger, Candida albicans and Staphylococcus aureus, and of influenza A virus. Massoialactone inhibits formation of the biofilm of S. aureus and has potential immunomodulatory, antiproliferative and anti-inflammatory uses.  

References

  • Synthesis of (±)​-​massoialactone. Crombie L. J Chem Soc. 1955, 2535. 
  • Clark D.V. and Whitfield F.B. Insect venoms, attractants and repellants. XI.7 Massoialactone from two species of formicine ants, and some observations on constituents of the bark oil of Cryptocarya massoia. Aust J Chem. 1968, 21, 2819.
  • In vitro antifungal and antiviral activities of γ- and δ-​lactone analogs utilized as food flavouring. Kishimoto N. et al. Biocontrol Sci. 2005, 10, 31.
  • In vitro evaluation of massoia bark essential oil and C-​10 massoialactone potency as immunomodulator. Permanasari P. et al. J Essential Oil-Bearing Plants 2017, 20, 459.
  • Synthesis and evaluation of (-​)​-​massoialactone and analogues as potential anticancer and anti-​inflammatory agents. Barros Maria E.S.B. et al. Eur J Med Chem. 2014, 76, 291.

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