LL 15G256α

LL 15G256α

$180.00 - 0.25 mg

$630.00 - 1 mg

All prices in Australian dollars

Code
BIA-L2381
Synonyms
BK 223A, LL 15156α, LL 15G256α, NG 012
CAS #
141731-76-2
Molecular Formula
C32H38O15
Molecular Weight
662.64
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in methanol or DMSO

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Application Notes

LL 15G256α is a macrocyclic polyester isolated from Hypoxylon oceanicum LL-15G256 using a bioassay guided approach. LL 15G256α is active in the os-1 assay, inhibiting biosynthesis of the fungal cell wall. LL 15G256α was patented by American Cyanamid in 1998 but did not reach the market.

References

  • Cell wall-​active antifungal compounds produced by the marine fungus Hypoxylon oceanicum LL-​15G256. I. Taxonomy and fermentation. Abbanat D. et al. J Antibiot. 1998, 51, 296.
  • Isolation and identification of antifungal polyesters from the marine fungus Hypoxylon oceanicum LL-​15G256. Schlingmann G. et al. Tetrahed. 2002, 58, 6825.
  • A modified screen for the detection of cell wall acting antifungal compounds. Kirsch D. & Lai M. J Antibiot. 1986, 39, 1620.

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