Khellin

Khellin

$85.00 - 5 mg

$300.00 - 25 mg

All prices in Australian dollars

Code
BIA-K2592
Synonyms
5,8-Dimethoxy-2-methyl-6,7-furanochromone
CAS #
82-02-0
Molecular Formula
C14H12O5
Molecular Weight
260.24
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in methanol or DMSO

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Product Data Sheet

Application Notes

Khellin is a constituent of the fruit of Ammi visnaga structurally related to psoralen. Khellin displays a range of pharmacological activities including anthelmintic, bronchodilator, vasodilator and antidiabetic properties. Khellin exhibits spasmolytic activity. Khellin is a photosensitising agent which has been used for the treatment of vitiligo in humans. Khellin may intercalate with DNA.

References

  • S 6. Furochromones. Part I. The synthesis of khellin. Baxter R.A. et al. J Chem Soc. 1949, S30-S33.
  • Pharmacological actions of the crystalline principles of Ammi visnaga. Anrep G.V. et al. J Pharmacy Pharmacol. 1949, 1, 164.
  • Phototherapeutic, photobiologic, and photosensitizing properties of khellin. Morliere D. et al. J Inv Dermatol. 1988, 90, 720.

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