IT-143-B is a rare, higher homologue of the piericidin class isolated from a Streptomyces sp. by Taiho Pharmaceuticals in collaboration with Chinese researchers in 1996. IT-143-B is active against the fungus, Aspergillus fumigatus, and the Gram-positive bacterium, Micrococcus luteus. IT-143-B is also active against KB carcinoma cells. Lack of availability until now has hindered exploration of its pharmacological effects.