Fumonisin B2

Fumonisin B2

$280.00 - 0.50 mg

$980.00 - 2.50 mg

All prices in Australian dollars

Code
BIA-F1258
CAS #
116355-84-1
Molecular Formula
C34H59NO14
Molecular Weight
705.8
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility.

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Product Data Sheet

Application Notes

Fumonisin B2 is a minor analogue of a family of potent mycotoxins produced by various Fusarium species, associated with animal toxicity worldwide. To date much of the research on the pharmacology of the fumonisins has focused on fumonisin B1. It is generally accepted that fumonisin B2 acts on ceramide biosynthesis, however, the pharmacology of the minor analogues is less well explored.

References

  • Structure elucidation of the fumonisins, mycotoxins from Fusarium moniliforme. Bezuidenhout S. C. et al., J. Chem. Soc. Chem. Commun. 1988, 743.
  • Inhibition of sphingolipid biosynthesis by fumonisins. Implications for diseases associated with Fusarium moniliforme. Wang E. et al., J. Biol. Chem. 1991, 266, 14486.
  • Inhibition of sphingolipid synthesis affects axonal outgrowth in cultured hippocampal neurons. Harel R. & Futerman A. H. J. Biol. Chem. 1993, 268, 14476.

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