Fumonisin B1
Fumonisin B1
$180.00 - 0.50 mg
$630.00 - 2.50 mg
All prices in Australian dollars
- Code
- BIA-F1257
- Synonyms
- Macrofusin
- CAS #
- 116355-83-0
- Molecular Formula
- C34H59NO15
- Molecular Weight
- 721.8
- Purity
- >95% by HPLC
- Long Term Storage
- -20°C
- Solubility
- Soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.
Download Data Sheets
Application Notes
Fumonisin B1 is a major analogue of a family of potent mycotoxins produced by various Fusarium species, associated with animal toxicity worldwide. In vitro, fumonisin B1 inhibits sphingosine N-acyl-transferase (ceramide synthase) and blocks the growth of axons.
References
- Structure elucidation of the fumonisins, mycotoxins from Fusarium moniliforme. Bezuidenhout S. C. et al., J. Chem. Soc. Chem. Commun. 1988, 743.
- Inhibition of sphingolipid biosynthesis by fumonisins. Implications for diseases associated with Fusarium moniliforme. Wang E. et al., J. Biol. Chem. 1991, 266, 14486.
- Inhibition of sphingolipid synthesis affects axonal outgrowth in cultured hippocampal neurons. Harel R. & Futerman A. H. J. Biol. Chem. 1993, 268, 14476.
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