ent-Epanorin

ent-Epanorin

$200.00 - 0.50 mg

$700.00 - 2.50 mg

All prices in Australian dollars

Code
BIA-E3089
Synonyms
D-Epanorin, (+)-Epanorin
CAS #
-
Molecular Formula
C25H25NO6
Molecular Weight
435.5
Purity
>95% by HPLC
Long Term Storage
Soluble in methanol and DMSO.

Download Data Sheets

Product Data Sheet

Application Notes

ent-Epanorin is the D-isomer of the naturally occurring L-form of epanorin. Epanorin is a member of the pulvinic acid family, with a tetronic acid core bound to the amino acid, L-leucine. ent-Epanorin is synthesised by reacting D-leucine methyl ester with pulvinic acid lactone. ent-Epanorin is moderately to weakly active against Gram positive organisms, B. subtilis and S. aureus, being more potent than epanorin. ent-Epanorin is more active than epanorin against G. duodenalis, but less active against murine myeloma NS-1.

References

  • Frank R.L. et al. (1950). The structures and syntheses of rhizocarpic acid and epanorin. J. Am. Chem. Soc., 72, 4454.
  • Palacios-Moreno J. et al. (2019). Epanorin, a lichen secondary metabolite, inhibits proliferation of MCF-7 breast cancer cells. Biol Res., 52, 55.
  • James P.J.C. et al. (2023). Synthesis, characterization, and bioactivity of the lichen pigments pulvinamide, rhizocarpic acid, and epanorin and congeners. J. Nat. Prod., 86, 550.

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