Desmethoxystreptonigrin, 10′-
Desmethoxystreptonigrin, 10′-
$300.00 - 0.50 mg
$1,050.00 - 2.50 mg
All prices in Australian dollars
- Code
- BIA-S1088
- CAS #
- 136803-89-9
- Molecular Formula
- C24H20N4O7
- Molecular Weight
- 476.4
- Purity
- >95% by HPLC
- Long Term Storage
- -20°C
- Solubility
- Soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.
Download Data Sheets
Application Notes
10'-Desmethoxystreptonigrin is a close analogue of streptonigrin produced by selected Streptomyces species. It is a moderately potent inhibitor of farnesylation of RAS P21 protein, 3-fold more active than streptonigrin. 10'-Desmethoxystreptonigrin has also been reported to have potent and broad spectrum antibacterial and antitumor activity.
References
- 10'-desmethyloxystreptonigrin, a novel analog of streptonigrin. Liu W.C. et al., J. Antibiot. 1992, 45, 454.
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