Chloramphenicol acetate

Chloramphenicol acetate

$180.00 - 5 mg

$630.00 - 25 mg

All prices in Australian dollars

Code
BIA-C1476
Synonyms
3-O-Acetylchloramphenicol, Chloramphenicol 3-acetate
CAS #
10318-16-8
Molecular Formula
C13H14Cl2N2O6
Molecular Weight
365.2
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.

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Application Notes

Chloramphenicol acetate is a naturally-occurring co-metabolite of chloramphenicol in Streptomyces venezuelae with albeit significantly lower potency. Chloramphenicol acetate is the major product of chloramphenicol acetyltransferase, the major resistance mechanism to chloramphenicol.

References

  • Isolation of 3′-O-acetylchloramphenicol: A possible intermediate in chloramphenicol biosynthesis. Gross F. et al., Bioorg. Med. Chem. Letters 2002, 12, 283.
  • Chloramphenicol acetyltransferase Shaw W.V. & Leslie A.G.W. Ann. Rev. Biophys. Biophys. Chem. 1991, 20, 363.

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