Aspochalasin M is a minor analogue of the aspochalasin class of anti-tumor actives discovered by researchers at the Institute of Marine Drugs and Food, China in 2009. Aspochalasin M was isolated from Spicaria elegans using an OSMAC (one species many compounds) fermentation strategy to explore the biosynthetic potential of the fungus. Interestingly, aspochalasin M itself was inactive against several tumor cell lines.