Panowamycin A

Panowamycin A

$195.00 - 0.25 mg

$685.00 - 1 mg

All prices in Australian dollars

Code
BIA-P2945
CAS #
1375224-55-7
Molecular Formula
C17H24O3
Molecular Weight
276.37
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO.

Download Data Sheets

Product Data Sheet

Application Notes

Panowamycin A is an isochroman isolated from a Streptomyces species by Omura and colleagues at the Kitasato Institute, Japan. Panowamycin A is moderately active against trypanosomes, with an IC50 of 0.40 μg/mL. Panowamycin A is an analogue of NFAT-133, a polyketide compound with immunosuppressive, antidiabetic and antitrypanosomal activities.

References

  • Panowamycins A and B, new antitrypanosomal isochromans produced by Streptomyces sp. K07-0010. Hashida J. et al. J Antibiot 2012, 65, 197.
  • Biosynthesis of the nuclear factor of activated T cells inhibitor NFAT-133 in Streptomyces pactum. Zhou W. et al. ACS Chem. Biol. 2020, 15, 12, 3217.

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