Tetracyclines are a class of linear tetracyclic antibiotics used for over 60 years with thousands of analogues prepared and published in the patent and scientific literature. Each of the ten analogues in the Tetracycline Analogue Set represent pivotal advances in the development of the class, with the analogues displaying a range of physico-chemical, potency, spectrum of action and cross-resistance profiles. The set is a useful tool in addressing current research questions on antibiotics using the resources accumulated since the discovery of chlortetracycline in 1948. | 1. Tetracycline – (CAS# 60-54-8) – Molecular Formula: C22H24N2O8 – Molecular Weight: 444.4 | 2. Chlortetracycline – (CAS# 57-62-5) – Molecular Formula: C22H23ClN2O8 – Molecular Weight: 478.9 | 3. Demeclocycline – (CAS# 127-33-3) – Molecular Formula: C21H21ClN2O8 – Molecular Weight: 468.9 | 4. Doxycycline – (CAS# 564-25-0) – Molecular Formula: C22H24N2O8 – Molecular Weight: 444.4 | 5. Meclocycline – (CAS# 2013-58-3) – Molecular Formula: C22H21ClN2O8 – Molecular Weight: 476.9 | 6. Methacycline – (CAS# 914-00-1) – Molecular Formula: C22H22N2O8 – Molecular Weight: 442.4 | 7. Minocycline – (CAS# 10118-90-8) – Molecular Formula: C23H27N3O7 – Molecular Weight: 457.5 | 8. Oxytetracycline – (CAS# 79-57-2) – Molecular Formula: C22H24N2O9 – Molecular Weight: 460.4 | 9. Sancycline – (CAS# 808-26-4) – Molecular Formula: C21H22N2O7 – Molecular Weight: 414.4 | 10. Tigecycline – (CAS# 220620-09-7) – Molecular Formula: C29H39N5O8 – Molecular Weight: 585.7