Lumichrome

Lumichrome

$230.00 - 25 mg

$65.00 - 5 mg

All prices in Australian dollars

Code
BIA-L2671
Synonyms
7,8-Dimethylisoalloxazine, NSC 96911, Riboflavin lumichrome
CAS #
1086-80-2
Molecular Formula
C12H10N4O2
Molecular Weight
242.23
Purity
>95% by HPLC
Long Term Storage
Soluble in methanol or DMSO

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Product Data Sheet

Application Notes

Lumichrome is a fluorescent, biologically active flavin produced by Micomonospora sp. and some other actinomycetes, fungi and plants, also formed by photolysis of riboflavin in acid or neutral solution. Lumichrome is a signalling molecule that enhances plant growth through a combination of enhanced cell division and cell enlargement and possible enhancement of photosynthesis. Lumichrome activates the LasR bacterial quorum sensing receptor and has anti-apoptotic activity via p53. Lumichrome inhibits osteoclastogenesis and bone resorption.

References

  • Ein neues Bestrahlungsprodukt des Lactoflavins: Lumichrom. Karrer P. et al. Helv Chim Acta 1934, 17, 1010.
  • Identification of lumichrome as a Sinorhizobium enhancer of alfalfa root respiration and shoot growth. Phillips D.A. et al. Proc Nat Acad Sci. 1999, 96, 12275.
  • The vitamin riboflavin and its derivative lumichrome activate the LasR bacterial quorum sensing receptor. Rajamani S. et al. Molecular Plant-Microbe Interactions 2008, 21, 1184.
  • Lumichrome inhibits osteoclastogenesis and bone resorption through suppressing RANKL-​induced NFAT activation and calcium signalling. Liu C. et al. J Cellular Physiol. 2018, 233, 8971.

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