IT-143B

IT-143B

$255.00 - 1 mg

$895.00 - 5 mg

All prices in Australian dollars

Code
BIA-I1829
Synonyms
IT-143-B
CAS #
183485-34-9
Molecular Formula
C28H41NO4
Molecular Weight
455.63
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO.

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Application Notes

IT-143-B is a rare, higher homologue of the piericidin class isolated from a Streptomyces sp. by Taiho Pharmaceuticals in collaboration with Chinese researchers in 1996. IT-143-B is active against the fungus, Aspergillus fumigatus, and the Gram-positive bacterium, Micrococcus luteus. IT-143-B is also active against KB carcinoma cells. Lack of availability until now has hindered exploration of its pharmacological effects.

References

  • IT-143-A and B, novel piericidin-group antibiotics produced by Streptomyces sp. Urakawa A. et al., J. Antibiot. 1996, 49, 1052.
  • Antibacterial, antifungal, and antitumor IT-143 substance of Streptomyces sp. Urakawa A. et al., Jpn. Kokai Tokkyo Koho 1997, JP 09249647.

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