Sartorypyrone B

Sartorypyrone B

$215.00 - 1 mg

$755.00 - 5 mg

All prices in Australian dollars

Code
BIA-S1803
CAS #
1452396-11-0
Molecular Formula
C30H42O7
Molecular Weight
514.65
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO.

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Application Notes

Sartorypyrone B is a pentacyclic meroterpenoid metabolite isolated from Aspergillus (syn. Neosartorya) species. While sartorypyrone B possesses no antibiotic activity against S. aureus, P. aeruginosa. B. subtilis and E. coli, it is nonethelesss capable of selective potentiation of ciprofloxacin, ampicillin, oxacillin and cefotaxime against E. coli, S. aureus and E. fecium. The mode of action of sartorypyrone B is not understood at this time.

References

  • Bioactive meroditerpenes and indole alkaloids from the soil fungus Neosartorya fischeri (KUFC 6344)​, and the marine-​derived fungi Neosartorya laciniosa (KUFC 7896) and Neosartorya tsunodae (KUFC 9213). Eamvijarn A. et al., Tetrahed. 2013, 8583.
  • Antibacterial and antibiofilm activities of tryptoquivalines and meroditerpenes Isolated from the marine-derived fungi Neosartorya paulistensis, N. laciniosa, N. tsunodae, and the soil fungi N. fischeri and N. siamensis. Nelson M. et al., Marine Drugs 2014, 12, 822.

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