Betulinic acid

Betulinic acid

$65.00 - 1 mg

$230.00 - 5 mg

All prices in Australian dollars

Code
BIA-B1758
Synonyms
(+)-Betulinic acid, Betulic acid, Lupatic acid, NSC 113090, β-Betulinic acid
CAS #
472-15-1
Molecular Formula
C30H48O3
Molecular Weight
456.71
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO.

Download Data Sheets

Product Data Sheet

Application Notes

Betulinic acid is a pentacyclic lupane terpene, first published in 1917. Betulinic acid is isolated as a constituent of various tree species, including birch. Betulinic acid has antiviral, antibacterial, antimalarial, Anti-inflammatory, anthelmintic and Antinociception properties. Betulinic acid induces apoptosis via caspase activation and also disrupts the mictochondrial membrane, induces DNA fragmentation and suppresses aerobic glycolysis via interaction with Cav-1. Derivatives of betulinic acid are active against bacterial biofilms.

References

  • Chemical studies of the Myrtaceae. II. The constituents of Syncarpia laurifolia Tenn. Hodgson D. et al., Aust. J. Chem. 1960, 13, 385.
  • Betulinic acid and its derivatives: A review on their biological properties. Yogeeswari P. & Sriram D., Curr. Med. Chem. 2005, 12, 657.
  • Betulinic acid suppresses breast cancer aerobic glycolysis via caveolin-1/NF-κB/c-Myc pathway. Jiao L. et al., Biochem. Pharmacol. 2019, 161, 149.

Other Products

Related products