Kumbicin C

Kumbicin C

$190.00 - 0.25 mg

$665.00 - 1 mg

All prices in Australian dollars

Code
BIA-K1640
CAS #
1878151-58-6
Molecular Formula
C28H24N2O3
Molecular Weight
436.5
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO.

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Application Notes

Kumbicin C is a bis-indolyl benzenoid isolated from a novel Aspergillus species, A. kumbius, by Piggott and co-workers in 2016. Structurally, kumbicin C is related to the petromicins found in a closely related species, A. muricatus and the asterriquinones from A. terreus. Biosynthetically, the unusual 2H-chromene ring system of kumbicin C is formed by cyclisation of the prenyl group of kumbicin D. Kumbicin C is active against tumor cell lines and bacteria at microgram potency.

References

  • Kumbicins A–D: bis-indolyl benzenoids and benzoquinones from an Australian soil fungus, Aspergillus kumbius. Lacey H.J. et al., Aust. J. Chem. 2016, 69, 152.

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