Thiocillin I

Thiocillin I

$280.00 - 0.50 mg

$980.00 - 2.50 mg

All prices in Australian dollars

Code
BIA-T1529
Synonyms
44-O-Demethylthiocillin II
CAS #
59979-01-0
Molecular Formula
C48H49N13O10S6
Molecular Weight
1160.4
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.

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Product Data Sheet

Application Notes

Thiocillin I is the simplest of the macrocyclic thiazole peptides, first isolated from Bacillus badius. The final structural assignment and total synthesis of thiocillin I was only completed in 2011. Thiocillin I was originally reported as a potent antibacterial but its biological activity has not been extensively investigated.

References

  • Isolation of three new antibiotics, thiocillin I, II and III, related to Micrococcin P. (Studies on antibiotics from the genus Bacillus VIII). Shoji J. et al., J. Antibiot. 1976, 29, 366.
  • Structural studies on thiocillins I, II and III (Studies on antibiotics from the genus Bacillus XXIX). Shoji J. et al., J. Antibiot. 1981, 34, 1126.
  • Total synthesis and complete structural assignment of Thiocillin I. Aulakh S. & Ciufolini M.A. J. Am. Chem. Soc. 2011, 133, 5900.

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