Lateropyrone

Lateropyrone

$190.00 - 5 mg

$665.00 - 25 mg

All prices in Australian dollars

Code
BIA-L1128
Synonyms
Avenacein Y, Antibiotic Y
CAS #
93752-78-4
Molecular Formula
C15H10O8
Molecular Weight
318.2
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in DMF or DMSO. Moderately soluble in methanol or ethanol. Poor water solubility.

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Application Notes

Lateropyrone is an unusual heterocyclic metabolite isolated from Fusarium avenaceum with antibacterial and antifungal activity. The metabolite was independently characterised as Antibiotic Y and found to be an important metabolite marker for strains of F. avenaceum. Lack of availability has hitherto restricted a more intensive investigation of this metabolite.

References

  • Pyrones. X. Lateropyrone, a new antibiotic from the fungus Fusarium lateritium Nees. Bushnell, G.W. et al., Can. J. Chem., 1984, 62, 2101.
  • Structural elucidation of an antibiotic from Fusarium avenaceum Fries Sacc.; an amended structure for lateropyrone. Gorst-Allman, C.P. et al., S. Afr. J. Chem., 1986, 39, 116.
  • Multiple regression analysis as a tool for the identification of relations between semi-quantitative LC-MS data and cytotoxicity of extracts of the fungus Fusarium avenaceum (syn. F. arthrosporioides). Uhlig S. et al., Toxicon. 2006, 48, 567.

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