Fusidate sodium

Fusidate sodium

$195.00 - 25 mg

$55.00 - 5 mg

All prices in Australian dollars

Code
BIA-F1259
Synonyms
Ramycin, NSC 56192, SQ 16603, SQ 16603
CAS #
751-94-0
Molecular Formula
C31H47NaO6
Molecular Weight
538.7
Purity
>98% by HPLC
Long Term Storage
Soluble in ethanol, methanol, DMF or DMSO. Good water solubility.

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Product Data Sheet

Application Notes

Sodium fusidate is the more water soluble sodium salt of fusidic acid, a steroidal metabolite of Fusidum coccineum which is a potent Gram positive antibiotic. Fusidic acid inhibits protein synthesis in prokaryotes by inhibiting the ribosome-dependent activity of G factor and translocation of peptidyl-tRNA. Fusidic acid also suppresses NO lysis of pancreatic islet cells.

References

  • Fusidic acid: a new antibiotic. Godtfredson W. O. et al., Nature 1962, 193, 987.
  • On the mode of action of fusidic acid. Harvey C. L. et al., Biochemistry 1969, 5, 3320.
  • Mechanism of protein synthesis inhibition by fusidic acid and related antibiotics. Tanaka N. et al., BBRC 1968, 30, 278.

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